Objective To investigate the effect of butylphthalide on the enzymic activity of CYP3A in rats. Methods Forty Wistar rats were randomly divided into 4 groups. The control group was intragastrically given vegetable oil; and the experimental group was subdivided into low, medium and high dose groups, intragastrically given butylphthalide 40, 80, and 160 mg · kg- 1(dissolved by vegetable oil), respectively. The experimental group and the control group were gavage dose for 5 days consecutively. Midazolam(4 mg ·...