【摘要】 目的探讨空腹血糖受损(IFG)对高血压患者左室扭转与解旋运动的影响,为防治高血压提供依据。方法入选140例高血压患者及37例正常对照组,高血压患者分为非空腹血糖受损组(非IFG组)66例、空腹血糖受损组(IFG组)74例。应用二维斑点追踪技术(STI)测量并计算左室短轴心尖部旋转角度峰值(PAR)及达峰时间(PART)、基底部旋转角度峰值(PBR)及达峰时间(PBRT)、左室整体扭转角度峰值(Ptw)及达峰时间(PtwT)、平均扭转速度(PtwM)、平均解旋速度(UntwM)、解旋率(UntwR)。结果 IFG组、非IFG组PBR(分别为-8.49°±3.06°、-8.36°±3.07°)、UntwR[分别为(40.86±14.92)、(44.46±16.56)%/ms]均小于对照组[(分别为-6.31°±2.08°、(51.62±17.23)%/ms],差异均有统计学意义(P<0.01);IFG组PAR(11.55°±4.63°)、Ptw(19.18°±5.18°)、PtwM[(56.37±15.19)°/s]、UntwM[(41.95±13.32)°/s]大于对照组[分别为8.20°±3.27°、13.82°±3.41°、(40.61±9.76)°/s和(27.68±8.80)°/s]、非IFG组[分别为10.03°±3.95°、17.49°±4.58°、(50.71±13.14)°/s和(35.69±11.87)°/s],差异均有统计学意义(P<0.01)。高血压患者Ptw与空腹血糖水平呈正相关(r=0.184,P<0.05)。结论 IFG可作为评价左室构型正常的高血压患者左室功能改变的预测因素。更多还原

【Abstract】 Objective To explore the effects of impaired fasting glucose(IFG) on left ventricular twisting and untwisting in hypertensive patients and to provide the basis for preventing and treating hypertension.Methods One hundred and forty hypertensive patients were divided into non-IFG group(66 cases) and IFG group(74 cases).A total of 37 healthy subjects were enrolled in this study.The speckle tracking imaging(STI) technique was used to measure the apical peak rotation(PAR),time to peak rotation(PART),basal peak rotation(PBR),time to peak on basal and apical plane(PBRT),LV peak twist(Ptw),time to peak(PtwT),mean untwisting(UntwM) and untwisting rate(UntwR).Results Compared with control group [-6.31°±2.08°,(51.62±17.23)%/ms,respectively],PBR and UntwR were significantly decreased in non-IFG group [-8.36°±3.07°,(44.46±16.56)%/ms,respectively]and IFG group [-8.49°±3.06°,(40.86 ±14.92)% /ms](P <0.01).PAR(11.55° ±4.63°),Ptw(19.18° ±5.18°),PtwM [(56.37 ±15.19)°/s] and UntwM [(41.95±13.32)°/s] in IFG group were significantly higher than those in control group [8.20°±3.27°,13.82°±3.41°,(40.61±9.76)°/s and(27.68±8.80)°/s,respectively] and non-IFG group [10.03°±3.95°,17.49°±4.58°,(50.71±13.14)°/s and(35.69±11.87)°/s,respectively](P<0.01).There was a positively correlation between Ptw and fasting bloodglucose level in hypertension patients(r=0.184,P<0.05).Conclusion IFG may be used to evaluate the prediction factors of left ventricular dysfunction in hypertension patients with normal geometric left ventricle.更多还原