【摘要】 刚地弓形虫(Toxoplasma gondii)是一种专性细胞内寄生原虫,能感染包括人在内的多种温血动物。免疫功能正常的机体感染弓形虫后,大多表现为隐性感染;但免疫功能低下的机体感染弓形虫后,可引起严重的弓形虫病。T细胞介导的免疫应答在控制弓形虫感染中发挥着重要的作用。本文就CD8+T细胞免疫应答在弓形虫感染方面的研究进展作一综述。更多还原

【Abstract】 Toxoplasma gondii is an obligate intracellular protozoan parasite, which infects warm-blooded animals including humans. T. gondii infection in the immune-competent individual is largely asymptomatic, but it can cause severe toxoplasmosis in immune-deficiency patients. T cell-mediated immunity plays an important role in resistance against T. gondii. Therefore, this review focuses on the progress of CD8+T cell-mediated immune response to T. gondii infection.更多还原