【摘要】 目的以HPLC指纹图谱为基础,对比分析准噶尔乌头同川乌和草乌,以及新疆常见的白喉乌头的色谱指纹图谱间的相似度,评价准噶尔乌头、白喉乌头与川乌、草乌的化学亲缘关系。方法通过Chem Pattern化学指纹图谱分析系统解决方案软件,将准噶尔乌头指纹图谱的共有模式分别同川乌、草乌、白喉乌头指纹图谱的共有模式进行聚类分析、相似度分析、主成分分析。结果化学指纹图谱分析系统解决方案软件分析表明,准噶尔乌头与草乌相似度较高,白喉乌头和川乌的相似度较高。结论初步确定新疆白喉乌头和已有法定标准的草乌相似度较高,值得进一步研究开发。更多还原

【Abstract】 OBJECTIVE To compare the HPLC fingerprints Aconitum soongaricum Stapf. with Aconitum carmichaelii Debx.,Aconitum kusnezoffii Reichb.,and another common radix aconite plant in Xinjiang,Aconitum leucostomum Worosch.,and analyze the degree similarity between different fingerprints. METHODS The HPLC fingerprint Aconitum soongaricum Stapf was established,and similarity analysis,cluster analysis and principal component analysis were carried out for the common patterns,Aconitum soongaricum Stapf and Aconitum carmichaelii Debx.,Aconitum kusnezoffii Reichb.,and Aconitum leucostomum Worosch. via the Chem Pattem chemical fingerprint analysis system software solutions. RESULTS The analysis showed that the similarities the mutual model reference fingerprints were higher between Aconitum soongaricum Stapf and Aconitum kusnezoffii Reichb. and between Aconitum leucostomum Worosch.and Aconitum carmichaelii Debx. CONCLUSION It is preliminarily determined that Aconitum soongaricum Stapf in Xinjiang had higher similarity with the legal standard Aconitum kusnezoffii Reichb.,which deserves further research and development.更多还原