【摘要】 目的分析我国药物治疗方案经济学评价的发展概况及存在的问题,并提出发展建议。方法检索2011年至2013年5月在国内专业学术期刊上发表的药物治疗方案经济学评价文献,从7个方面进行统计分析。结果共收集文献389篇,研究者以药剂师为主,对照研究以2种药物和2组药物最多,成本-效果分析法占绝对比重,大部分研究以药费作成本指标,对不良反应情况进行描述,对药价进行敏感度分析。结论药物治疗方案经济学评价研究还存在很多不足之处,需要加强对《中国药物经济学评价指南》的研究,建立良好的合作交流平台,明确研究角度,选择适宜的对照治疗方案,选用适当的评价分析方法,确定成本测算范围,正确处理不良反应问题,进行合理的敏感度分析,并注重研究的科学性、规范性。更多还原

【Abstract】 Objective To analyze the status and existing problems of economic evaluation of medicine therapeutic scheme in China and put forward suggestions for its development. Methods Economic evaluation literature on medicine therapeutic scheme published in domestic academic journals from 2011to May 2013was searched and analyzed from seven aspects.Results A total of 389articles were collected;the researchers were mainly pharmacists;the comparisons in most controlled studies were between two kinds of drugs or two groups of drugs;cost-effectiveness analyses accounted for an absolute proportion;most of the studies took drug fees as cost indicators,and described the situation of adverse reactions,and carried out sensitivity analysis on the drug prices.Conclusion There are still many shortcomings in economic evaluation of medicine therapeutic scheme.We should strengthen the research of China Guidelines for Pharmacoeconomic Evaluations,establish a good platform for cooperation and communication,define the direction of research,choose appropriate treatment,select appropriate evaluation methods,determine the scope of the cost estimates,correctly deal with adverse reactions,reasonably analyze the sensitivity problem,and enhance the scientific and normative research.更多还原