【摘要】 目的 探讨经阴道三角形子宫切除术的临床可行性及对卵巢功能的影响。方法 选择2006年1月至2007月1月在河北省人民医院妇产科因妇科良性疾病需要切除子宫并强烈要求保留宫颈的50例患者作为观察组,行经阴道=i角彤子宫切除术,同期采用传统经阴道子宫切除术的50例患者作为对照组。比较不同术式手术时问、术中f『I血量、术后并发症发生率;以及术前1个月、术后第l、2、3年卵泡中晚期血清雌二醇、卵泡刺激素(FSH)、黄体生成素(LH)、泌乳素水平。结果 观察组的术前、术后l、2、3年FSH分别为(6.7±2.1)、(6.9±2.O)、(7.0±2.2)、(7.6±2.0)U/L,雌二醇分别为(160±17)、(157±23)、(156±20)、(150±23)ng/L,手术前后FSH、雌二醇与术前比较差异无统汁学意义(尸>O.05)÷对照组患者术前、术后l、2、3年FSH分别为(7.0±2.1)、(6.8±2.0)、(18.4±5.9)、(35.9±2.1)U/L,雌二醇分别为(177±21)、(15l±17)、(IlO±19)、(80±18)n∥L,术后2、3年对照组FSH水平明显高于术前,雌二醇水平明显低于术前,差异有统计学意义(P<0.05)。观察组和对照组术中m衄量分刖为(62±19)、(89±18)ml,差异有统计学意义(Jp<0.05),2组患者术后恢复排气时间、术后下床时问比较差异无统计学意义(P>0.05),术后并发症发生率分别为8.0%(4/50)、10.O%(5/50),差异无统计学意义(P>0.05)。结论 经阴道三角形子宫切除术不增加手术难度和术后并发症的发生率;保留卵巢的血液供应及功能,在保护年轻患者卵巢功能、延缓卵巢功能早衰方面存在着明显优势,更多还原

【Abstract】 Objective To explore the clinical feasibility of triangle hysterectomy and its effect on the ovaries.Methods The medical records of 50 women who had vaginal triangle hysterectomy were detected.50 women who had vaginal hysterectomy were as the control group.The operation time,the amount of hemorrhage and the complications for both groups were compared.Levels of follicle stimulating hormone(FSH),luteinizing hormone(LH),prolactin(PRL) at 1 month pre-operation,1 year,2 years,and 3 years post-operation were evaluated as well.Results In the study group,the serum FSH before operation,1 year,2 years,3 years after operation was(6.7 ±2.1),(6.9 ±2.0),(7.0 ±2.2),(7.6 ±2.0) U/L;estradiol were(160 ±17),(157 ±23),(156 +20),(150 ±23)ng/L.There was no significant difference in the serum FSH and estradiol in study group(P >0.05).In the control group the serum FSH before operation,1 year,2 years,3 years after operation was(7.0 ±2.1),(6.8 ±2.0),(18.4 ±5.9),(35.9 ±2.1)U/L;estradiol were(177 ±21),(151±17),(110 ±19),(80 ±18) ng/L.There was a significant change at 2,3 years in the control group(P < 0.05).Bleeding amount in the observation group and control group respectively was(62 ±19) and(89 ± 18) ml;the difference was statistically significant(P<0.05).There was no significant difference in the operation time,the amount of hemonhage and the complications[8.0%(4/50) vs 10.0%(5/50)]in both groups(P > 0.05).Conclusions The vaginal triangle hysterectomy is a safe method.It can preserve the blood-supply and the function of ovaries.更多还原