【摘要】 目的 探讨地佐辛对鞘内舒芬太尼分娩镇痛所致瘙痒的治疗作用。方法 选取90例美国麻醉师协会分级Ⅰ~Ⅱ级、单胎、足月(≥37周)、枕前位妊娠拟经阴道分娩,行鞘内注射舒芬太尼5μg分娩镇痛后24 h内瘙痒的产妇,完全随机分成2组(每组45例)。地佐辛组静脉注射地佐辛5 mg(1 ml),0.9%氯化钠注射液组静脉注射0.9%氯化钠注射液1 ml。瘙痒评分、镇痛评分、镇静评分每5分钟记录1次,记录30 min。结果 地佐辛组瘙痒的治疗有效率明显高于0.9%氯化钠注射液组[80.0%(36/45)比15.6%(7/45),P<0.01],2组的镇痛评分比较差异无统计学意义[(2.2±0.5)分比(2.04±0.3)分](P>0.05),2组的镇静评分比较差异有统计学意义(P<0.05)。结论 地佐辛5 mg静脉注射可以有效地治疗鞘内舒芬太尼分娩镇痛所引起的瘙痒。更多还原

【Abstract】 Objective To investigate the effect of dezocine on the spinal sulfentanyl-induced pruritus during labor analgesia.Methods Ninety patients with american society of anesthesiologists physical status 1-2,nulliparous and undergoing a spontaneous labor(≥37 weeks of gestation) with a live,singleton fetus,receiving spinal sulfentanyl-induced prutitus during labor analgesia(in postoperative 24 h) were randomly allocated to receive5 mg dezocine(1 ml)(dezocine group,45 cases)or 1 ml 0.9%sodium chloride injection(0.9%sodium chloride injection group,45 cases)intravenously.Pruritus,sedative and the level of postoperative pain were assessed every 5 min till the end of the study period(30 min).Results The treatment success rate in the dezocine group was higher than that in the 0.9%sodium chloride injection group[80.0%(36/45) vs 15.6%(7/45),P <0.01].Other side effects,such as decreased analgesia,were not significantly different between groups.Sedation scores between the two groups was statistically significant[(2.2±0.5) scores vs(2.0±0.3) scores].Conclusion Dezocine is an efficient drug treatment for spinal sulfentanyl-induced pruritus during labor analgesia.更多还原