【摘要】 目的:观察三拗片联合头孢呋辛钠治疗肺气肿的疗效。方法:选取我院肺气肿患者150例,根据随机数字表法均分为三拗片组、头孢呋辛钠组和联合组。三拗片组患者给予口服三拗片,2粒/次,3次/d;头孢呋辛钠组患者给予静脉滴注含头孢呋辛钠2 g的生理盐水100 ml,2次/d;联合组同时给予三拗片口服和头孢呋辛钠静脉滴注,用法与用量与其他两组一致。3组患者均以1周为1个疗程,治疗2个疗程后,对3组患者的治疗效果及肺功能改善情况进行比较。结果:联合组的总有效率为92.0%,显著高于三拗片组(82.0%)和头孢呋辛钠组(80.0%),差异具有统计学意义(P<0.05);联合组动脉血氧分压(PaO2)、二氮化碳分压(PaCO2)、第1秒用力呼气容积(FEV1.0)和第1秒用力呼气容积占预计值百分比(FEV1%)均优于三拗片组和头孢呋辛钠组,差异具有统计学意义(P<0.05)。结论:三拗片联合头孢呋辛钠治疗肺气肿,疗效较好,患者呼吸功能得到了很大程度的改善。更多还原

【Abstract】 OBJECTIVE:To observe the clinical efficacy of San’ao tablets combined cefuroxime sodium in the treatment of pulmonary emphysema. METHODS:150 patients with pulmonary emphysema collected from our hospital were randomly divided into San’ao tablets group,cefuroxime sodium group and combination group. San’ao tablets group was given San’ao tablets,2 pieces/time,p.o.,3 times a day;Cefuroxime group was given normal saline containing cefuroxime 100 ml,i. p.,twice a day;Combination group was given San’ao tablets and normal saline containing Cefuroxime,same usage and dosage as above 2 groups. A treatment course of 3 groups last for a week. After 2 cycles of therapy,therapeutic efficacy and the improvement of pulmonary function were compared among 3 groups. RESULTS:The total effective rate was 92.0% in combination group,which was significantly higher than San’ao tablets group(82.0%) and cefuroxime sodium group(80.0%),there was statistical significance(P<0.05);PaO2,PaCO2,FEV1.0 and FEV1% of combination group were significantly better than those of other 2 groups,there was statistical significance(P<0.05). CONCLUSIONS:San’ao tablets combined with western medicine antibiotics is effective for pulmonary emphysema and can improve the respiratory function of patients greatly.更多还原