Sonoporation mediated by microbubbles is being extensively studied as a promising technology to facilitate gene/drug delivery to cells. However, the theoretical study regarding the mechanisms involved in sonoporation is still in its infancy.Microstreaming generated by pulsating microbubble near the cell membrane is regarded as one of the most important mechanisms in the sonoporation process. Here, based on an encapsulated microbubble dynamic model with considering nonlinear rheological effects of both shell...
【英文摘要】
Sonoporation mediated by microbubbles is being extensively studied as a promising technology to facilitate gene/drug delivery to cells. However, the theoretical study regarding the mechanisms involved in sonoporation is still in its infancy.Microstreaming generated by pulsating microbubble near the cell membrane is regarded as one of the most important mechanisms in the sonoporation process. Here, based on an encapsulated microbubble dynamic model with considering nonlinear rheological effects of both shell...
【基金】
Projects supported by the National Basic Research Program,China(Grant No.2011CB707900);
the National Natural Science Foundation of China(Grant Nos.81127901,81227004,81271589,11374155,11161120324,11074123,11174141,11274170,11104140,11474001,and 11474161);
the National High Tech Research and Development Program,China(Grant No.2012AA022702);
the Program for New Century Excellent Talents in University of Ministry of Education of China(Grant No.NCET-11-0236)
【更新日期】
2014-12-31
【分类号】
R318.01
【正文快照】
Wang Li(王莉)a),Tu Juan(屠娟)a),Guo Xia-Sheng(郭霞生)a),Xu Di(许迪)b),and Zhang Dong(章东)a)Sonoporation mediated by microbubbles is being extensively studied as a promising technology to facilitate gene/drugdelivery to cells.However,the theoretical study
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