【摘要】 目的探讨神经外科术后非细菌感染患者粒细胞CD64指数阳性的原因。方法对2014年3月至2014年7月神经外科295例手术治疗患者的术后粒细胞CD64指数结果进行临床分析。结果共24例患者术后粒细胞CD64指数阳性,其中细菌感染患者13例,非细菌感染但粒细胞CD64指数阳性患者11例。11例患者粒细胞CD64指数均为轻度升高,结果为3.18~7.00。分析这11例结果发现,非感染阳性的原因主要为手术应激(6例,55.0%)、病毒感染(3例,27.0%)、真菌感染(2例,18.0%)。结论粒细胞CD64指数作为提示外科术后细菌感染的指标时,当检测结果位于3.18~7.00之间时需要结合临床其它指标如影像学资料、C-反应蛋白、白介素-6、降钙素原等综合评价,以免造成临床误诊。更多还原

【Abstract】 Objective To investigate the cause of increase in the neutrophil CD64 index in the patietsn with nonbacterial infectionafter neurosurgery.MethodsThe neutrophil CD64 index was determined by flow cytometry and calculated in 295 patients whounderwent neurosurgery from March, 2014 to July, 2014. The causes of the increase in neutrophil CD64 index were analyzed.Results The neutrophil cd64 index increased in 24 of these 295 patients. Of 24 patients with high neutrophil CD64 index, 14 had bacterialinfection and 11 not. The neutrophil CD64 indexes 2ranged from 3.18 to 7.00 in the positive CD64 index 11 patients without bacterialinfection, in whom, the cause of the increase in neutrophil CD64 index included surgical stress(54.5%, 6/11), virus infection(27.3%, 3/11) and fungal infection(18.2%, 2/11).ConclusionThe meanings of the positive neutrophil CD64 index should be carefully assessed incombination with imaging data, c-reactive proten, interleukinn-6, procalcitoninto and so on in order to avoid misdisagnosis when theneutrophil CD64 index ranged from 3.18 to 7.00.更多还原