【摘要】 目的 探讨抗酸染色在结核病病理诊断中的意义。方法 回顾性分析2000—2012年兰州军区兰州总医院病理诊断结核病并有抗酸染色结果的914例(男485例,女429例)患者的病理资料。使用SPSS 20.0软件进行统计学处理,以X~2检验对计数资料进行统计分析,P<0.05为差异有统计学意义。结果 914例结核病患者结核分枝杆菌抗酸染色阳性率为31.95%(292/914)。支气管结核和肠结核患者结核分枝杆菌抗酸染色阳性率分别为48.24%(41/85)和58.06%(18/31),高于肺结核抗酸染色阳性率(33.33%,72/216),差异均有统计学意义(X~2值分别为5.777、7.159,P值均<0.05);结核性胸膜炎(19.78%,18/91)、脊柱结核(16.52%,19/115)和关节结核阳性率(12.00%,6/50)低于肺结核患者结核分枝杆菌抗酸染色阳性率(33.33%,72/216),差异均有统计学意义(72值分别为5.676、10.640和8.916,P值均<0.05)。男、女患者结核分枝杆菌抗酸染色阳性率分别为30.93%(150/485)和33.10%(142/429),性别对抗酸染色结果差异无统计学意义(X~2=0.494,P>0.05)。结论 抗酸染色仍是诊断结核病的有效确切手段,病变部位不同,抗酸染色阳性率亦有差异。更多还原

【Abstract】 Objective To investigate the value of acid-fast staining in pathological diagnosis of tuberculosis(TB).Methods Nine hundred and fourteen TB cases(485 male,429 female)with acid-fast staining admitted to our hospital from 2000 to 2012 were analyzed retrospectively.SPSS 20.0 software was used for statistical analysis.Statistical comparisons were performed using X~2 test,and P value less than 0.05 was considered statistical significant.Results Among the 914 patients positive rate of acid-fast staining was 31.95%(292/914).The positive rates of endobronchial TB,intestinal TB were 48.24%(41/85),58.06%(18/31)respectively,which were higher than that of pulmonary TB(33.33%,72/216)with statistical significant differences(X~2=5.777,P<0.05;X~2=7.159,P<0.05);while the positive rates of pleural TB,spinal TB and osteoarthral TB were 19.78%(18/91),16.52%(19/115),12.00%(6/50)respectively,which were lower than that of pulmonary TB,with statistical significant differences(X~2=5.676,P<0.05;X~2=10.640,P<0.05;X~2=8.916,P<0.05).The positive rates in male and female patients were 30.93%(150/485)and 33.10%(142/429)respectively,with no statistical significance difference(X~2=0.494,P>0.05).Conclusion Acid-fast staining is still an effective method for the diagnosis of TB.The positive rate can be affected by the lesion site.更多还原