【摘要】 目的探讨机械通气患者发生胃肠道功能障碍的因素及其与临床预后的关系。方法收集机械通气非胃肠道疾病患者72例,根据是否发生胃肠道功能障碍分为胃肠道功能障碍组(A组,32例)和非胃肠道功能障碍组(B组,40例)。分析两组的机械通气指标、胃肠道功能障碍发生危险因素及与临床预后之间的关系。结果 A组的年龄、机械通气时间、APACHEⅡ评分、手术科室所占比例、ICU住院时间、血乳酸水平、MODS发生率均显著高于B组(P<0.05);胃肠道功能障碍与MODS发生率及死亡率呈正相关(P<0.05)。结论胃肠道功能障碍是造成机械通气患者预后不良的重要原因,早期积极防治胃肠道功能障碍、适时肠内营养支持有利于改善临床预后。更多还原

【Abstract】 Objective To investigate the factors of gastrointestinal dysfunction and its relationship with clinical prognosis in patients with receiving mechanical ventilation.Methods Seventy-two patients with mechanical ventilation and non-gastrointestinal diseases were collected and divided into gastrointestinal dysfunction groups(A group,32 cases) and non-gastrointestinal dysfunction group(group B,40 cases).The mechanical ventilation index,risk factors and the relationship between clinical outcomes and gastrointestinal dysfunction of the two groups were analyzed.Results The age,duration of mechanical ventilation,APACHE Ⅱ score,proportion of surgical departments,ICU length of stay,blood lactate levels,MODS incidence indicated thatthe rate of group A were significantly higher than those in group B(P < 0.05);The relationship between gastrointestinal dysfunction and MODS incidence and ratios of mortality showed positive correlated(P < 0.05).Conclusion Gastrointestinal dysfunction is an important cause of poor prognosis in patients receiving mechanical ventilation.These data suggested that early prevention of aggression to gastrointestinal dysfunction and application of enteral nutrition help to improve clinical outcomes.更多还原