【摘要】 目的了解海口市性病门诊就诊者的泌尿生殖道支原体感染和耐药情况,为临床合理用药提供参考依据。方法用支原体培养及药敏试剂盒对本性病门诊的4 046份尿道/宫颈分泌物标本进行支原体培养、鉴定和药敏试验。结果支原体阳性1 431份(35.37%),其中UU阳性1 077份(26.62%),MH阳性43份(1.06%),UU+MH阳性311份(7.69%)。而且女性患者支原体阳性率(53.20%)明显高于男性(28.10%),差异有统计学意义(P<0.01)。药敏结果:UU,MH,UU+MH对交沙霉素、强力霉素、美满霉素较敏感,对环丙沙星耐药率最高。结论海口市性病门诊就诊者泌尿生殖道支原体感染以UU为主,交沙霉素、强力霉素、美满霉素是治疗本地区泌尿生殖道支原体感染的首选药物。更多还原

【Abstract】 Objective To investigate the urogenital mycopiasma infection and its drug sensitivity in patients from STD clinic,and provide guidance for a reasonable application of antibiotics. Methods The mycoplasma cultivation and commercial kit for drug susceptibility test were performed in 4 046 patients with genitourinary tract infection. Results The total positive rate of mycoplasma infection was 35. 37%. The positive rate of UU,MH,and UU + MH was 26. 62%,1. 06%,7. 69%,respectively. The mycoplasma infection rate was 28. 10%in male and 53. 20% in female. There was significant difference between male and female( P < 0. 01). Josamycin,minocyclin and doxycycline were more effective drug against UU,MH,UU + MH infection. The drug resistant rate of UU to ciprofloxacin was highest. Conclusion The urogenital mycoplasma infection results mainly from UU infection in patients from STD clinic in Haikou. Josamycin,doxycycline and minocyclin are the first line drugs for urogenital mycoplasma infection in Haikou.更多还原