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乙酰丙酮铜催化合成N-取代芳基酰胺
Copper(Ⅱ)acetylacetonate-catalyzed synthesis of N-substituted aryl amides
【摘要】 针对以钯、镍等过渡金属为催化剂合成N-取代芳基酰胺化合物具有价格昂贵、毒性较强、适用范围小等缺陷,提出一种以乙酰丙酮铜为催化剂合成N-取代芳基酰胺的方法.该方法成本低廉,对环境友好,反应条件温和,为N-取代芳基酰胺的工业合成增添了新途径.
【Abstract】 For palladium,nickel and other transition metals as catalyst for synthesis of N-substituted aryl amide compounds,it has the disadvantages of expensive,larger toxicity and small scope of application.The paper developes a method of synthesis of N-substituted aryl amide catalyzed by copper acetylacetonate with low-cost,environmentally benign and mild reaction conditions.It adds new ways for the industrial synthesis of N-substituted aryl amide.
【关键词】 卤代芳烃;
乙酰丙酮铜;
N-取代芳基酰胺;
交叉偶联;
【Key words】 aryl halides; copper(Ⅱ)acetylacetonate; N-substituted aryl amides; cross-coupling;
【Key words】 aryl halides; copper(Ⅱ)acetylacetonate; N-substituted aryl amides; cross-coupling;
【基金】 国家自然科学基金资助项目(21173182);江苏省自然科学基金资助项目(BK2010307);2012年度江苏省“企业博士集聚计划”资助项目
- 【文献出处】 扬州大学学报(自然科学版) ,Journal of Yangzhou University(Natural Science Edition) , 编辑部邮箱 ,2014年02期
- 【分类号】O621.36
- 【被引频次】2
- 【下载频次】138