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沙门菌的药敏结果及临床治疗研究

Susceptibility of Salmonella and Clinical Research

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【作者】 王玲

【Author】 WANG Ling;Shenxian Traditional Chinese Medicine Hospital;

【机构】 山东省莘县中医医院

【摘要】 目的了解沙门菌的药敏试验结果以及临床治疗。方法对我院2010年~2012年收治的122例伤寒患者进行治疗,对患者进行血液抽取,检测沙门菌的药敏性。此外,将患者随机分成观察组和对照组,每组各61例。观察组采用氯霉素药物治疗,对照组采用阿莫西林药物治疗,对比两组的治疗结果。结果沙门菌是主要的致病菌,该沙门菌对阿莫西林、头孢噻吩等药物的耐药性较强。对氯霉素、头孢噻肟、环丙沙星等药物的耐药性较弱。此外,观察组治疗的有效率达到98.36%,对照组治疗的有效率达到39.34%,组间对比,差异有统计学意义(P<0.05)。结论沙门菌对氯霉素和氟喹诺酮等药物的耐药性较低,并具有较高的敏感性,因此氯霉素和氟喹诺酮成为治疗沙门菌的有效用药。

【Abstract】 Objective To study the salmonella antimicrobial susceptibility test results and clinical treatment. Methods From 2010 to 2012 in our hospital treated 122 cases of patients with typhoid fever treatment, the patients with blood extraction, detection of salmonella susceptibility. In addition, patients were randomly divided into observation group and control group, 61 cases in each group. Observation group using chloramphenicol drug treatment, control group adopts amoxicillin drugs, compared two groups of treatment results. Result A major pathogen Salmonella, the Salmonella bacteria to amoxicillin, cephalothin and other drug resistance is strong. Chloramphenicol, cefotaxime, ciprofloxacin drug resistance is weak. In addition, the observation group treatment efficiency reached 98.36%, the efficiency of the control group reached 39.34%, between-group comparison, the difference was statistically significant(P <0.05). Conclusion Salmonella to chloramphenicol and fluoroquinolone drugs such as low resistance, and has high sensitivity, chloramphenicol and fluoroquinolone become effective drug for the treatment of salmonella.

【关键词】 沙门菌药敏结果药物临床治疗
【Key words】 SalmonellaSusceptibility resultsDrugsClinical treatment
  • 【文献出处】 中国医药指南 ,Guide of China Medicine , 编辑部邮箱 ,2014年20期
  • 【分类号】R446.5
  • 【被引频次】1
  • 【下载频次】78
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