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活血化瘀法对改善慢性阻塞性肺病急性发作期低氧血症的临床研究

Clinical Research Method to Improve Blood Circulation and Chronic Obstructive Pulmonary Disease with Acute Exacerbation of Hypoxemia

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【作者】 李晶陈翻享肖超烈钱旭胜连乐燊

【Author】 LI Jing;CHEN Fan-xiang;XIAO Chao-lie;QIAN Xu-sheng;LIAN Le-shen;Dongguan Traditional Chinese Medicine Hospital;

【机构】 广东省东莞市中医院

【摘要】 目的探讨活血化瘀法对改善慢性阻塞性肺病急性发作期(AECOPD)低氧血症的疗效。方法对97例AECOPD患者随机分为治疗组和对照组,治疗组51例,采用活血化瘀法配合常规西药治疗;对照组46例,采用常规西药治疗。观察不同时期D-二聚体、凝血功能水平、全血黏度和血气分析等指标。结果两组治疗后第7天D-二聚体及氧分压指标明显改善,且治疗组疗效优于对照组,有统计学意义(P<0.05);两组治疗后第7天血液黏稠度和血氧饱和度均有改善,无统计学意义(P>0.05);余监测指标间未见明显差异,无统计学意义(P>0.05)。结论活血化瘀法可以改善AECOPD患者低氧血症。

【Abstract】 Objectives To study the curative effect of activating blood circulation method on the improvement of hypoxemia in Acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods 97 AECOPD patients were randomly assigned to treatment group and control group. 51 patients in the treatment group were mainly treated with activating blood circulation method and supplemented with regular western medicines while 46 patients in the control group were exclusively treated with regular western medicines. D-dimer, coagulation function, blood viscosity, blood gas analysis and other indexes were tested and examined during observation in the present trial. Results On the seventh day following treatment with either method, the indexes of both D-dimer and partial pressure of oxygen were significantly improved in both groups. And the recovery treatment group was better than control group, with statistical significance(P<0.05). In addition, blood viscosity and oxygen saturation were improved in patients from either group, without statistical significance(P>0.05). There was no significant difference for the rest monitoring indexes between the two groups, without statistical significance(P>0.05). Conclusion Activating blood circulation method can improve hypoxemia in AECOPD patients.

【基金】 2010年广东省东莞市科技局课题《活血化瘀法对改善慢性阻塞性肺病急性发作期低氧血症的临床研究》(201010515000270)
  • 【文献出处】 中国医药指南 ,Guide of China Medicine , 编辑部邮箱 ,2014年17期
  • 【分类号】R259
  • 【被引频次】18
  • 【下载频次】117
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