【摘要】 目的探讨血清同型半胱氨酸(homocysteine,HCY)对急性心肌梗死(acute myocardial infarction,AMI)的评估和预测价值。方法收集92例本院心血管内科住院的AMI患者(AMI组),同期60例心血管内科门诊随访体检者作为对照(对照组)。采用高频超声检测两组双侧颈动脉内膜中层厚度(IMT)、粥样斑块及其稳定性,测定HCY水平,并进行分析比较。结果①AMI组颈动脉斑块发生率高于对照组(P<0.05),不稳定性斑块发生率及血清HCY水平显著高于对照组(P<0.01)。②HCY与斑块性质之间具有很强的关联性(r=0.975)。结论血清HCY水平检测评估和预测AMI的价值可能更高于颈动脉不稳定性斑块的检出。更多还原

【Abstract】 Objective To evaluate the relationship between serum levels of homocysteine( HCT) and acute myocardial infarction( AMI). Methods Ninety-two hospitalized AMI patients were designed as AMI group and 60 followed-up cases in out-patient clinic of cardiovascular medicine were used as control group. Carotid IMT and plaque stabilization were assessed by high frequency ultrasonography. Serum levels of HCY were measured. Results ①The incidence rate of plaque in the AMI group was higher than that in the control group( P < 0. 05). The incidence of unstable plaque and the serum HCY level in the AMI group were significantly higher than that in the control group( P < 0. 01). ② The serum level of HCY was correlated with stabilization of carotid atherosclerotic plaque( r = 0. 975). Conclusion The clinical value of HCY level for AMI may be possibly higher than that of the presence of carotid atherosclerotic unstable plaques for AMI.更多还原