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祛风胜湿颗粒挥发油与β-环糊精包合工艺研究

Study on Inclusion Process of Qufeng Shengshi Granules Volatile Oil with β- Cyclodextrin

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【作者】 任燕茹秦海军张毅马玲

【Author】 Ren Yanru;Qin Haijun;Zhang Yi;Ma Ling;College of Pharmacy,Anhui University of Chinese Medicine;Anhui Provincial Institute of Materia Medica;Anhui Provincial Key Laboratory of Research and Development of Chinese Medicine;

【机构】 安徽中医药大学药学院安徽省药物研究所安徽省中药研究与开发重点实验室

【摘要】 目的研究祛风胜湿颗粒挥发油与β-环糊精包合的最佳工艺。方法采用饱和水溶液法,以包合物收得率和挥发油包合率作为评价指标。结果包合最佳工艺是,挥发油∶环糊精为1∶8,包合温度50℃,包合时间1 h。结论优选的工艺条件易于控制,稳定可行。

【Abstract】 Objective To study the optimum process of Qufeng Shengshi Granules volatile oil with β-cyclodextrin inclusion. Methods The saturated aqueous solution method was adopted with the inclusion compound yield and the volatile oil inclusion rate as the evaluation indexes. Results The optimum inclusion process was as follows: the ratio of volatile oil to β-cyclodextrin was 1 ∶ 8,the inclusion temperature was50 ℃ and the inclusion time was 1 h. Conclusion The optimized process conditions are easy to be controlled,stable and feasible.

  • 【文献出处】 中国药业 ,China Pharmaceuticals , 编辑部邮箱 ,2014年12期
  • 【分类号】TQ461
  • 【被引频次】2
  • 【下载频次】45
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