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特发性膜性肾病的治疗进展
Progress of Treatment for Idiopathic Membranous Nephropathy
【摘要】 特发性膜性肾病(IMN)是导致成人肾病综合征的常见原因之一。其自然病程差异悬殊,部分患者未经治疗可自发缓解,还有一些患者则会持续进展,使得临床肾脏科医师对治疗抉择陷于两难境地。目前诸多研究表明,激素及免疫抑制剂治疗是有效的,但过早使用这些药物也可能使患者暴露于不必要的不良反应中。近年来,基于IMN的治疗研究成为热点,该文就IMN的治疗进展予以综述。
【Abstract】 Idiopathic membranous nephropathy( IMN) is one of the most common causes of nephrotic syndrome in adults. The natural progress of the disease may vary a lot in different individuals,while a number of untreated patients may have a spontaneous remission,other patients will progress overtime,which put clinical nephrologists in a dilemma when facing the treatment options. evident number of studies indicate that therapies based on corticosteroids and immunosuppressive drugs are effective,but the early use of these agents may cause unnecessary adverse effects. Studies based on the IMM treatment has become a hot topic,and here is to make a review of the IMM treatment.
【Key words】 Idiopathic membranous nephropathy; Therapy; Immunosuppressive drugs;
- 【文献出处】 医学综述 ,Medical Recapitulate , 编辑部邮箱 ,2014年07期
- 【分类号】R692.3
- 【被引频次】14
- 【下载频次】426