【摘要】 回顾性分析乳腺浸润性微乳头状癌(IMPC)的临床病理特征。选取河北医科大学第四医院乳腺中心手术切除并经病理证实的女性原发性乳腺癌共3 383例,筛选出符合IMPC为实验组,同期乳腺浸润性导管癌(IDC)为对照组。结果显示,本组IMPC 167例,占同期乳腺癌4.94%,年龄29岁~80岁,中位年龄54岁。淋巴结转移者共135例,占80.8%,淋巴结转移数目≥4个共105例,占62.9%,HER2阳性率58.7%,与IDC组相比差异均有统计学意义(P<0.05)。IMPC为一种少见类型的浸润性乳腺癌,具有淋巴管侵袭性强、淋巴结转移率高的生物学行为。应与其他类型肿瘤进行鉴别,明确诊断。更多还原

【Abstract】 To analyze the clinicopathologic features invasive micropapillary carcinoma(IMPC)of the breast.3383 women patients of primary breast cancer which were diagnosed by pathology in the 4th Hospital of Hebei Medical University were analyzed.The IMPC as the experiment group,the invasive ductal carcinoma(IDC)which diagnosed in the same period was selected as the control group.Of the 3383 patients,4.94%(167/3383)was IMPC,the age range was 29~80years with a median age was 54 years.80.8%(135/167)of the patients with positive lymph nodes,and 62.9%(105/167)of patients with 4or more positive lymph nodes.58.7%of patients were HER-2-positive,all of the index had statistically significant different compared with the IDC group.The IMPC is a kind of rare invasive breast cancer with such biologic behaviors as a strong attacking on lymphatic and high probability of lymph node transfer.It should be diagnosed definitely by identified with other tumors.更多还原