【摘要】 目的:通过测量DTI参数(ADC和FA值)在脊髓型颈椎病中的变化,探讨DTI对检测脊髓型颈椎病(CSM)脊髓损伤的价值。材料与方法:对30例健康志愿者和50例脊髓型颈椎病患者进行常规MRI及DTI检查。根据T2WI图像颈髓病变区信号不同,将CSM患者分为颈髓病变区高信号组(A组,17例)和等信号组(B组,33例),正常对照组(C组,40例)。测量DTI参数,比较不同组别ADC值和FA值的变化。结果:常规T2WI等信号患者(B组),虽然常规T2WI没有显示出病变脊髓异常信号改变,但是DTI参数值出现变化,FA值降低,提示病变脊髓各向异性减低;ADC值升高,反映各向同性增高。常规T2WI高信号患者(A组),FA值进一步减低,ADC值更加升高。ADC值、FA值在A,B,C组中的差别均有统计学意义。结论:通过脊髓型颈椎病两组的研究,显示DTI能在常规T2WI尚未出现异常信号之前就能检测颈髓的较为早期的损伤,DTI较常规MRI检测脊髓慢性损伤更敏感,DTI能更早、更精确地发现脊髓型颈椎病的脊髓病变。更多还原

【Abstract】 Objective:The application values of DTI on the injury of the cervical spinal cord in cervical spondylotic myelopathy was explored by DTI evaluation.Material and method:A total of 30 healthy controls and 50 patients with cervical spondylotic myelopathy was performed on conventional MRI and DTI.According to the signal of the damage cord on T2 WI,the patients were divided into three groups:hyperintense(group C,17cases),isointense(group B,33cases).control group(group A,30 cases).To study the features of DTI and compare the values of ADC and FA of diffcrent groups.Results:FA maps showed orange or yellow at the compression site of spinal cord,suggested FA values decreasing.ADC maps exhibited inhomogeneous high intensity at involved spinal cord.DTI was sensitive in detecting spinal cord damage and could assess subtle structural damage and changes of the CSM.Conclusion:DTI can delect cervical spinal cord earlier injury before the abnormal signal conventional T2 WI has not yet appeared:DTI is more sensitive than conventional MRI to detect chronic spinal cord injury:DTI can be earlier and more accurately discover cervical myelopathy spinal cord lesions.更多还原