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左炔诺孕酮宫内缓释系统治疗子宫肌瘤伴月经过多的疗效

Clinical outcomes of levonorgestrel-intrauterine releasing system in treating uterine fibroids with menorrhagia

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【作者】 徐青陈艳骆潇洁刘青青史颖莉

【Author】 XU Qing;CHEN Yan;LUO Xiaojie;Department of Family Planning,Affiliated Nanjing Maternity and Child Health Care Hospital,Nanjing Medical University;

【机构】 南京医科大学附属南京妇幼保健院计划生育科

【摘要】 目的观察左炔诺孕酮宫内缓释系统(LNG-IUS)治疗子宫肌瘤伴月经过多的临床效果。方法子宫肌瘤患者52例,于月经3-5d刮除大部分内膜后放置LNG-IUS。置器后第1、3、12个月随访,观察月经量、血红蛋白水平,B超测量子宫容积、瘤体积,记录置器后脱落率及不良反应的发生率。结果与置器前比较,置器后患者月经量减少、血红蛋白水平升高、子宫容积缩小(P<0.05);但子宫肌瘤体积无明显变化。结论宫腔放置LNG-IUS能有效减少患者月经量,改善贫血症状,缩小子宫容积,减少不良反应。

【Abstract】 Objective To observe the clinical outcomes of the levonorgestrel-intrauterine releasing system(LNG-IUS)in treating uterine fibroids with menorrhagia.Methods The LNG-IUS was placed into the uterine of 52patients with uterine fibroids in 3-5days of menstruation after scrapping the endometrium.The changes of menstrual blood volume,hemoglobin levels,uterine volume and myoma volume were measured in the 1st,3rd and 12th month after LNG-IUS putting.The expulsion rate and adverse events were recorded as well.Results Compared to before,the menstrual blood volume was reduced,hemoglobin level elevated and the uterus volume decreased after the 1st month(P<0.05),but the volume of uterus fibroid was not changed significantly.Conclusion The LNG-IUS placement can effectively reduce the menstrual blood volume,raise hemoglobin level and reduce the uterus volume with little adverse events in the patients with uterine fibroids and menorrhagia.

【基金】 国家自然科学基金(81202042);南京市医学科技发展基金(QRX11212)
  • 【文献出处】 江苏医药 ,Jiangsu Medical Journal , 编辑部邮箱 ,2014年01期
  • 【分类号】R737.33
  • 【被引频次】8
  • 【下载频次】83
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