【摘要】 目的比较重组人酸性成纤维细胞生长因子(rh-a FGF)与碱性成纤维细胞生长因子(b FGF)治疗浅Ⅱ度烧伤的临床疗效差异。方法入选6个研究医院254例门诊浅Ⅱ度烧伤患者。治疗组给予银离子敷料联合a FGF(清创时清洗治疗,清创后给予喷雾治疗)。对照组给予银离子敷料联合b FGF(给药方法同a FGF)。记录创面愈合时间及愈合后的色素沉着情况。结果rh-a FGF治疗后完全愈合时间为(7.1±1.5)d,b FGF治疗后愈合时间为(9.2±1.8)d,两组随访过程中感染发生率分别为1.5%,9.2%,两组比较具有统计学差异(P>0.05)。但两组色素沉着评分分别为(2.2±1.6)分,(3.0±1.4)分,不具有统计学差异(P<0.05)。结论 a FGF可促进浅Ⅱ度烧伤愈合,预防感染,疗效优于b FGF,安全性相似。更多还原

【Abstract】 【Objective】To compare recombinant human acidic fibroblast growth factor(rh-a FGF) and basic differences in the clinical efficacy of a fibroblast growth factor(b FGF) treatment of superficial Ⅱ degree burns. 【Methods】The study enrolled six outpatient hospital 254 cases of superficial Ⅱ degree burns patients. The treatment group received a silver ion dressing combined a FGF(debridement cleaning treatment,aerosol therapy given after debridement). The control group received a silver ion dressing Joint b FGF(method of administration with a FGF). Record pigmentation situation and heal the wound healing time after. 【Results】rh-a FGF completely healed after treatment time was 7.1±1.5 d,after b FGF treatment healing time was 9.2±1.8 d,the two groups during follow-up the incidence of infection was 1.5%,9.2%,respectively,the two groups was statistically difference(P>0.05). But the two groups pigmentation scores were 2.2±1.6,3.0±1.4 d,does not have a statistically significant difference(P<0.05). 【Conclusion】a FGF can promote healing of superficial II degree burns,infection prevention,more effective than b FGF,similar safety.更多还原