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首发抑郁障碍患者认知功能损害的病例对照研究

A Case-Control Study of Cognitive Impairment in Depression Patients

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【作者】 杨铭哲梁云海林昭宇吴逢春

【Author】 YANG Mingzhe;LIANG Yunhai;LIN Zhaoyu;WU Fengchun;Guangzhou Psychiatric Hospital;

【机构】 广东省广州市精神病医院

【摘要】 目的探讨首发抑郁障碍患者认知功能损害的特点。方法随机将我院收治的确诊为首发抑郁障碍的患者91例作为研究组,并按方便抽样选取本院正常健康职工90例作为对照组,对比两组的认知功能状况。结果研究组RBANS评分均明显低于对照组(P<0.05);研究组WCST完成分类数与概念化百分数均明显较对照组低(P<0.05),而总测验数则明显高于对照组(P<0.05)。结论首发抑郁障碍患者的全面认知功能存在程度不一的损害。

【Abstract】 Objective To investigate the characteristics of cognitive impairment of first episode depression patients.Methods A case-control study was used to analyze 91 patients with first episode depression and 90 cases of healthy controls.The cognitive functions were compared.Results The study group had lower RBANS scores(P <0.05) than the control group.WCST: the study group had lower number of categories completed and conceptualization percentages,but the total score was significantly higher than that of the control group(P <0.05).Conclusions The overall cognitive function of patients with first episode depression has varying degrees of damage.

【关键词】 抑郁障碍认知功能病例对照
【Key words】 DepressionCognitive functionCase-control
  • 【文献出处】 临床医学工程 ,Clinical Medicine & Engineering , 编辑部邮箱 ,2014年07期
  • 【分类号】R749.41
  • 【被引频次】1
  • 【下载频次】74
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