【摘要】 目的分析抗凝药物在早发型子痫前期中的应用效果。方法选择2012年6月至2013年6月间在本院接受治疗的68例早发型子痫前期患者作为研究对象,并随机分为对照组和观察组各34例,对照组患者使用临床常规治疗,观察组患者在常规治疗的基础上使用抗凝药物治疗。比较两组患者的子痫发病率、新生儿低体重及窒息发生率等情况差异。结果观察组妊娠终止孕周(33.5±1.0)周、Apagar评分≥7分(82.35%)明显高于对照组;子痫发病率(5.88%)、新生儿低体重(8.82%)及窒息发生率(2.94%)均明显低于对照组(P<0.05)。结论对于早发型子痫前期患者而言,早期采用小剂量阿司匹林抗凝治疗可以有效降低患者的子痫发生率,优化新生儿结局,具有积极的临床意义,值得推广使用。更多还原

【Abstract】 Objective To analyze the application effect of anticoagulant drug in the early-onset preeclampsia. Methods Sixty-eight patients with early-onset preeclampsia treated in our hospital from June 2012 to June 2013 were selected as research subjects, and divided into the observation group and control group, with 34 cases in each group. All patients received the conventional therapy, while patients in the observation group received the anticoagulation therapy additionally. The incidence of eclampsia, low birth weight and neonatal asphyxia were compared between two groups. Results The terminated gestational week was(33.5 ± 1.0) weeks, Apagar score ≥7 points was 82.35% in observation group, significantly higher than those of control group(P <0.05). The incidence of eclampsia, low birth weight and neonatal asphyxia was 5.88%, 8.82% and 2.94% in observation group respectively, significantly lower than those of control group(P <0.05). Conclusions For patients with early-onset preeclampsia, the early use of low-dose aspirin for anticoagulant therapy can reduce the incidence of eclampsia, optimize neonatal outcomes. It has positive clinical significance, and is worthy of clinical promotion.更多还原