【摘要】 目的探讨中药联合重组白介素-11治疗难治性特发性血小板减少性紫癜的临床疗效和护理措施。方法将52例肾性贫血难治性特发性血小板减少性紫癜患者随机分成2组,治疗组26例给予重组人白介素-11(巨和粒)治疗,皮下注射,每天1次,连用14 d,每个月为1个疗程,并口服中药汤剂(由黄芪、生地、仙鹤草、水牛角、丹皮、紫珠草等组成),日1剂,早晚分服;对照组26例只给予重组人白介素-11(巨和粒)治疗。2组均配合专科护理干预措施,均治疗2个月。结果治疗组总有效率为88.5%,对照组为65.4%,2组比较差异有统计学意义(P<0.05)。结论中药联合重组白介素-Ⅱ对难治性特发性血小板减少性紫癜有显著疗效。更多还原

【Abstract】 Objective To explore the clinical curative effect and nursing of Chinese medicine combined with recombinant interleukin-2 in treating refractory idiopathic thrombocytopenic purpura.Methods 52 renal anemia refractory idiopathic thrombocytopenic purpura patients were randomly divided into treatment group and control group. The treatment group with 26 cases was given subcutaneous injection of recombinant human interleukin-2( Juhe Granule) for 1 time daily,continuous treatment lasted for 14 days per month and 1 months was a course of treatment. Besides,Chinese medicine decoction( composed of radix astragali,radix rehmanniae,herba agrimoniae,buffalo horn,cortex moutan,callicarpa macrophylla vahl,etc) was orally taken for 1 agent daily for 2 times in the morning and evening. The control group with 26 cases was given only recombinant human interleukin-2( Juhe Granule). The course of the treatment in the two groups was lasted for 2 months and nursing intervention measures were conducted during the treatment. Results The effective rate was 88. 5% in the treatment group and 65. 4% in the control group. Comparison of the two groups showed that the difference was statistically significant( P < 0. 05). Conclusion Chinese medicine combined with recombinant interleukin-2 in treating refractory idiopathic thrombocytopenic purpura has significant curative effect.更多还原