【摘要】 目的探讨尿白蛋白/肌酐比值(UACR)与2型糖尿病(T2DM)患者视网膜病变(DR)的关系。方法选取2型糖尿病患者213例,根据UACR检测结果将其划分为UACR正常组、UACR微量异常组和UACR大量异常组。检测并比较3组患者眼部视网膜病变发生情况。结果 UACR检测值异常的2组患者的FBC、PBC、糖化血红蛋白含量和收缩压、舒张压等指标检测值均较正常组患者显著偏高(P<0.05);UACR正常组患者的DR发生率为15.9%,而UACR微量异常组DR的发生率为43.1%,UACR大量异常组DR的发生率为60.3%。UACR异常的患者较正常组的患者DR的发病率明显升高(P<0.05),且UACR的值越大,DR的发病率越高。结论糖尿病视网膜病变与患者肾脏病变之间存在密切关系。UACR异常的患者DR的发病风险较高,因而临床可以将UCER值作为视网膜病变发生的早期诊断指标。更多还原

【Abstract】 Objective To investigate the relationship between ratio of urinary albumin /creatinine( UACR) and retinopathy( DR) in patients with type 2 diabetes mellitus( T2DM). Methods213 patients with type 2 diabetes were divided into normal UACR group,abnormal UACR minor group and abnormal UACR plenty group according to the UACR level. The occurrence of retinopathy in patients of three groups were detected and compared. Results FBC,PBC,glycosylated hemoglobin levels,systolic blood pressure,diastolic blood pressure and other indicators of patients were significantly higher in the UACR abnormal groups than normal group( P < 0. 05). DR rate of UACR normal group was 15. 9%,the rate in abnormal UACR minor group was 43. 1%,the rate in UACR abnormal group was 60. 3%. So the difference was significant since the morbidity of DR in abnormal groups was higher than the normal group( P < 0. 05),and the larger the value of UACR,the higher the occurrence of DR. Conclusion There were close relationship between retinopathy and nephropathy in patients. The risk of DR patients with abnormal UACR is higher. Therefore,UCER test can be used for the early diagnosis of retinopathy.更多还原