【摘要】 目的探讨血清黄体酮对早期宫内妊娠及异常妊娠的预测意义。方法选择该院住院部2012年10月至2013年5月收治的早孕妇女214例(停经时间为4~8周),采用化学发光法检测血清黄体酮、血清绒毛膜促性腺激素(HCG),动态监测并联合B超对早期正常妊娠及异常妊娠进行筛查、随访。结果 214例患者中早期宫内妊娠110例,自然流产47例,异位妊娠57例。三组研究对象的年龄、β-HCG、黄体酮水平比较,差异均有统计学意义(P<0.05);logistic回归分析显示黄体酮与早孕期妊娠结局相关;当黄体酮大于63.6 nmol/L时自然流产和异位妊娠的发生率明显降低;理想的维持妊娠的黄体酮水平应为63.6~95.4 nmol/L。结论监测早孕期血清HCG和黄体酮水平对妊娠结局有预测价值。更多还原

【Abstract】 Objective To investigate the predictive value of serum progesterone(P) to early uterine pregnancy and abnormal pregnancy. Methods A total of 214 women with early pregnancy(menopause time was 4-8 weeks),who were received in the hospital from October 2012 to May 2013,were selected and detected on P,human chorionic gonadotropin(HCG) by chemiluminescence method,and dynamic monitoring combined with B ultrasound was adopted for screening and follow-up. Results Among the 214 cases,there were 110 cases with early intrauterine pregnancy,47 cases with spontaneous abortion and 57 cases with ectopic pregnancy. The comparison of age,β-HCG and P among the three kinds of pregnancy showed statistically significant dif ference(P<0.05);Logistic regression analysis showed that P level was associated with the outcomes of the early pregnancy,when P>63.6 nmol/L,the incidence of the spontaneous abortion and ectopic pregnancy was significantly reduced,and the ideal level for maintaining the pregnancy of P was 63.6-95.4 nmol/mL. Conclusion It is an effective way to predict the pregnancy outcomes by monitoring the serum HCG and P level in early pregnancy.更多还原