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幽门螺杆菌根除治疗对糖尿病性胃轻瘫疗效的影响

Curative effect of helicobacter pylori eradication in treating of diabetic gastroparesis

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【作者】 陈鸿唐珍珍陶娅

【Author】 Chen Hong;Tang Zhenzhen;Tao Ya;Sichuna Mianyang 404 Hospital/the Second Affiliated Hospital of North Sichuan Medical College;

【机构】 绵阳四O四医院川北医学院附属第二医院

【摘要】 目的分析幽门螺杆菌根除治疗对糖尿病性胃轻瘫临床疗效的影响。方法以2011年1月至2013年1月收治的100例糖尿病性胃轻瘫患者为研究对象,采用随机分配原则,将患者分为对照组和试验组各50例。对照组患者给予莫沙必利治疗,试验组患者在对照组治疗基础上增加幽门螺杆菌根除治疗,即增加阿莫西林、克拉霉素以及奥美拉唑治疗。比较两组患者的临床疗效及不良反应发生情况。结果试验组患者的临床总有效率(96.0%,48/50)明显高于对照组(80.0%,40/50),差异有统计学意义(P<0.05);两组不良反应比较,差异无统计学意义(P>0.05)。结论对糖尿病性胃轻瘫患者实施幽门螺杆菌根除治疗效果显著,值得在临床推广和普及。

【Abstract】 Objective To analyze the curative effect of helicobacter pylori(Hp) eradication therapy in patients with diabetic gastroparesis. Methods A total of 100 patients with diabetic gastroparesis,who were treated in the hospital from January 2011 to January 2013,were collected and dividec into control group and experiment group based on the principle of random distribution,50 cases in each group. The control group was treated with mosapride,while the experiment group was added with Hp eradication based on the treatment of control group,which is added with amoxicillin,clarithromycin and omeprazole for treatment. The clinical curative effect and adverse reactions between the two groups were observed and compared. Results The total effective rate of experimental group(96.0%,48/50) was obviously higher than that of control group(80.0%,40/50) with statistically significant difference(P<0.05). There was no statistically significant difference on adverse reactions between the two groups(P>0.05). Conclusion The clinical research results show that the implementation of helicobacter pylori eradication in patients with diabetic gastroparesis treatment is with significant effect and worth promoting and popularizing.

  • 【文献出处】 现代医药卫生 ,Journal of Modern Medicine & Health , 编辑部邮箱 ,2014年11期
  • 【分类号】R587.2
  • 【被引频次】4
  • 【下载频次】56
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