Value of combined detection of human epididymis secretory protein 4,lysophosphatidic acid and cancer antigen 125 in the diagnosis of epithelial ovarian cancer
Objective To evaluate the value of combined detection of human epididymis secretory protein 4(HE4),lysophosphatidic acid(LPA) and cancer antigen 125(CA125) in the diagnosis of epithelial ovarian cancer. Methods A total of80 cases consist of 30 cases with epithelial ovarian cancer( epithelial ovarian cancer group),30 cases with ovarian benign tumor(ovarian benign tumor group) and 20 healthy people who had physical examination during the same period(healthy control group) in Department of Gynecology and Obste...
【更新日期】
2014-11-27
【分类号】
R737.31
【正文快照】
卵巢癌发病隐匿,且缺乏早期诊断方法,待发现时70%已属临床晚期[1]。糖类抗原125(cancer anti-gen 125,CA125)是最常用的诊断卵巢癌的肿瘤标志物,但血清CA125在检测上皮性卵巢癌时特异性和敏感性均较低[2]。近年发现人附睾蛋白4(human ep-ididymis secretory protein 4,HE4)和溶
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