【摘要】 目的分析食物不耐受特异性IgG抗体在珠海地区婴幼儿的分布特征。方法选择302例门诊有食物过敏症状或体征的婴幼儿患者为研究对象,通过酶联免疫法检测患儿血清中14种食物过敏原特异性IgG抗体。比较IgG抗体在不同年龄组和性别组之间的阳性率差异,并比较食物不耐受程度。结果 302例患儿中,283例(93.70%)特异性IgG呈阳性;总阳性率女性(94.78%)高于男性(93.05%),但男女组间差异无统计学意义(P>0.05)。男女组中IgG阳性率前4位均依次为鸡蛋>牛奶>鳕鱼>大豆。2个月至1岁、2岁组和3岁组特异性IgG总阳性率分别为90.24%、97.35%和91.89%,其差异无统计学意义(P>0.0 5)。不同食物的阳性强度分布不同。结论临床上具有某些过敏症状或体征的婴幼儿患者中普遍存在食物不耐受现象;不同项目总阳性率与阳性程度存在差异。食物不耐受在不同年龄和性别间差异不显著。更多还原

【Abstract】 Objective To analyze the food intolerance specific IgG antibody distribution of infants in Zhuhai area.Methods A total of 302 infant patients of out-patient clinic who had a food allergy symptoms or signs as the research object.Enzyme linked immunosorbent assay detection was used to detect 14 kinds of food allergen specific IgG antibody in serum of the infants.IgG antibody positive rate differences between different age groups and gender groups and the extent of food intolerance were compare.Results In the 302 patients,283 cases(93.70%) were positive for specific IgG; the total positive rate of female(94.78%) was higher than male(93.05%).However,the difference between male and female groups was not statistically significant(P > 0.05).The four highest positive rate of specific IgG were egg > milk > morrhua > soybean in both male and female.The positive rate of specific IgG in 2 months to 1 year old group,2 years old group and 3 years old group were90.24%,97.35% and 91.89%,and the difference among the groups was not statistically significant(P > 0.05).The extent of food intolerance in different food was different.Conclusion Food intolerance has certain allergy symptoms or signs in clinical pediatric patients in general.There are differences in different projects about the total positive rate and positive degree.Food intolerance has no significant difference between different ages and gender.更多还原