【摘要】 目的比较欧洲营养风险筛查2002(Nutritional Risk Screening,NRS2002)在新疆地区不同民族肝癌患者营养筛查的结果差异及其与预后的相关性。方法采用连续定点抽样的方法,收集2010年1-12月在新疆医科大学第一附属医院肿瘤中心就诊的肝癌患者351例新疆不同民族肝癌患者,在入院次日清晨采用NRS2002量表进行营养筛查,进行后续随访,比较不同民族患者的营养状况及其与预后的关系。结果 351例肝癌患者均完成调查,BMI评定为营养不足、超重和肥胖的发生率分别为11.68%、6.55%、4.84%,男性分别为12.99%、6.50%、12.33%,女性分别为6.76%、6.76%、6.76%,男性患者和女性患者差异无统计学意义(P=0.431)。汉族患者分别为12.59%、6.64%、3.15%,维吾尔族患者分别为11.76%、8.82%、14.71%,其他少数民族患者分别为3.23%、3.23%、9.67%,汉族和维吾尔族患者筛查结果差异有统计学意义(P=0.017);新疆肝癌患者NRS2002筛查提示营养风险的发生率为58.69%,男性患者为64.26%,女性患者为47.30%,不同性别肝癌患者营养风险发生率差异有统计学意义(P=0.011)。汉族患者营养风险发生率为60.84%,维吾尔族患者营养风险发生率为35.29%,其他少数民族营养风险发生率为64.52%,汉族患者营养风险发生率高于维吾尔族患者(P=0.006);生存分析显示,有营养风险的患者预后较差(P<0.05)。结论不同民族肝癌患者的营养状况存在差异,并且这种差异与预后相关。更多还原

【Abstract】 Objective To investigate the nutritional status of patients with hepatocellular carcinoma in Xinjiang area,and to compare the differences of results and prognosis between the patients from different nationalities with hepatocellular carcinoma in Xinjiang area.Methods Using continuous fixed-point sampling method,the samples from 351 patients who met the inclusion criteria in the hospital were collected and were screened according to NRS2002 scale.Then we did follow-up,and compared their nutritional status and its relationship with their prognosis.Results 351 cases of liver cancer patients completed the survey,and BMI assessment for malnutrition,overweight and obesity rates were 11.68%,6.55%,4.84%.The percentage of male patients were 12.99%,6.50%,12.33%;the percentage of female patients were 6.76%,6.76%,6.76%(P=0.431).Han patients were 12.59%,6.64%,3.15%;Uygur patients was 11.76%,8.82%,14.71%(P=0.017).NRS2002 screening suggests malnutrition rate was 58.69%,64.26%in male,47.30 in female(P=0.011),60.84%in Han,35.29%in Uygur,64.52%in other minorities(P=0.006).The survival analysis showed that low NRS2002 score is one of the risk factors in the poor prognosis of HCC patients(P <0.05).Conclusion There is a difference in nutrition status between different ethnic patients with liver cancer,and this difference is related to the prognosis.更多还原