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23例心脏永久起搏器装置相关感染的临床特点与处理

The clinical characteristics and treatment for pacemaker device-related infection in 23 patients

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【作者】 李永江师俊亮汤宝鹏李晋新张宇许国军李耀东张燕一张疆华周贤惠

【Author】 LI Yongjiang;SHI Junliang;TANG Baopeng;LI Jinxin;ZHANG Yu;XU Guojun;LI Yaodong;ZHANG Yanyi;ZHANG Jianghua;ZHOU Xianhui;Department of Critical Care Medicine,Sixth Division Hospital,Xinjiang Production and Construction Corps;Xinjiang Xinyuan County People′s Hospital;The Heart Center,The First Affiliated Hospital of Xinjiang Medical University;

【机构】 新疆生产建设兵团第六师医院重症医学科新疆新源县人民医院新疆医科大学第一附属医院心脏中心

【摘要】 目的探讨永久心脏起搏器装置相关感染的临床特征、治疗方法及其预后。方法选择2003年1月-2012年12月在兵团第六师医院、新源县人民医院、新疆医科大学第一附属医院心脏中心的2 972例安装永久心脏起搏器装置病人,因"永久心脏起搏器装置相关感染"的有23例患者,回顾性分析永久心脏起搏器系统相关感染的临床特点、处理及预后。结果单纯囊袋局部感染21例,囊袋感染合并全身感染2例。2例经静脉使用抗生素及局部换药,3例行局部清创,18例行整个起搏装置移除与清创。局部清创组2例感染复发(66.7%),装置移除组1例感染复发(5.6%)。起搏器装置感染的发生率为0.77%,起搏器装置首次植入感染的发生率为0.69%,起搏器装置更换后的感染发生率为1.36%,首次植入起搏器患者感染发生率较起搏器更换患者低,差异无统计学意义(P=0.17)。结论永久心脏起搏器相关感染是起搏器植入后的严重并发症。单纯局部清创感染复发风险较高,永久起搏装置移除是最佳的治疗方案。

【Abstract】 Objective To analyse retrospectively the clinical characteristics of cardiac pacemaker devices-related infections.Methods 23patients who have cardiac pacemaker devices-related infections were enrolled in this retrospective study.Results Pocket infection in 21cases,systemic infection in 2cases.The incidence of pacemaker devices-related infection was 0.77%.The incidence of infection was 0.69%for the implant patients vs 1.36%for replacement patients,and there were significant differences in two groups(P =0.17).For the treatment,2patients received only intravenous antibiotics and local treatment;3patients underwent local debridement;18patients removed and re-implanted pacemaker.There were 2cases of recurrent infection(66.7%)in local debridement group and 1case of recurrence in device removal group(5.6%).Conclusion Pacemaker-related infection is a serious complication after implantation,and the best treatment for this situation is to remove the pacemaker device.

【关键词】 起搏器感染治疗
【Key words】 pacemakerinfectiontherapy
【基金】 新疆维吾尔自治区自然科学基金(2011211A066)
  • 【文献出处】 新疆医科大学学报 ,Journal of Xinjiang Medical University , 编辑部邮箱 ,2014年01期
  • 【分类号】R541.7
  • 【被引频次】4
  • 【下载频次】162
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