【摘要】 目的:探讨年龄≤35岁急性心肌梗死(AMI)患者的危险因素及冠状动脉病变特点。方法:回顾我院2010年10月至2011年12月,行冠状动脉造影的年龄≤35岁96例(A组)和200例年龄>35岁AMI患者的临床和冠状动脉造影资料,分析其冠心病危险因素及冠状动脉病变特点等。结果:与年龄>35岁AMI患者相比,≤35岁患者在男性、超质量、肥胖、吸烟及急性ST段抬高型心肌梗死比例较高(96.5%vs.70.0%;75%vs.45.5%;35.4%vs.17.5%;72.9%vs.49.0%;93.8%vs.79.5%,P<0.05),而高血压、糖尿病及血脂异常较低(P<0.05)。≤35岁患者中,12例患者冠状动脉造影正常,单支病变发生率高;而年龄>35岁AMI患者以3支血管病变为主。结论:≤35岁AMI患者的主要危险因素是吸烟和肥胖,大部分为ST段抬高型AMI,病变以单支冠状动脉病变为主。更多还原

【Abstract】 Objective: To investigate the risk factors and coronary characteristics of patients aged 35 years or younger with acute myocardial infarction( AMI). Methods: We retrospectively enrolled 96 consecutive( ≤ 35years old) and 200 patients( >35years old) with clinical diagnosis of AMI from October 2010 to December 2011. All patients underwent coronary angiology,and the clinical risk factors and coronary features were assessed. Results: Compared AMI group( > 35 years old),the proportion of male cases,overweight and obese patients,smoking cases were higher( 96. 5% vs. 70. 0%; 75% vs. 45. 5%; 35. 4% vs. 17. 5%; 72. 9% vs. 49. 0%; 93. 8% vs. 79. 5%,P < 0. 05). And the proportion of cases with hypertension,diabetes and dyslipidemia were lower( 20. 8% vs. 46. 0%; 14. 6% vs. 41. 5%; 6. 3% vs. 38. 5%,P < 0. 05) in patients aged 35 years or younger with AMI. There were 12 cases( 6. 1%) without obvious coronary stenosis and coronary artery lesions were mainly single vessel lesion( 55. 2%),while in AMI patients more than 35 years old,coronary artery lesions were mainly triple vessel disease( 57. 5%). Conclusion: Smoking and obesity were the most important modifiable risk factors in patients aged 35 years or younger with AMI. Those patients were mainly presented with ST-segment elevated myocardial infarction and single-vessel coronary artery disease.更多还原