【摘要】 目的分析持续气道正压通气(CPAP)治疗阻塞性睡眠呼吸暂停综合征(OSAS)合并高血压患者的临床效果。方法随机选取OSAS合并高血压患者96例,将其均分为治疗组和对照组。治疗组患者行CPAP治疗;对照组患者行常规治疗。采用多导睡眠检测仪监测患者的睡眠并记录分析,测定患者的血氧饱和度、鼾声变化和呼吸暂停低通气指数(AHI)等指标,并比较2组患者收缩压和舒张压的变化情况。结果治疗组收缩压由(161.7±11.9)mmHg(1 mmHg=0.133kPa)降低为(125.4±10.3)mmHg,对照组收缩压由(162.1±12.0)mmHg降低为(140.9±11.3)mmHg。治疗组AHI由(45.9±18.7)次/h降低为(4.5±3.1)次/h,对照组由(46.0±18.8)次/h降低为(21.4±7.9)次/h。治疗组ESS总分由(19.8±4.3)分降低为(4.5±3.1)分,对照组由(20.0±4.4)分降低为(11.7±4.0)分。结论 CPAP治疗OSAS合并高血压患者有很好的临床效果。它可以有效改善患者嗜睡症状,降低其AHI,还可以降低患者的血压,使其恢复到健康水平。更多还原

【Abstract】 Objective It is to observe the clinical effect of continuous positive airway pressure( CPAP) on the treatment of obstructive sleep apnea syndrome( OSAS) patients with hypertension. Methods 96 OSAS patients with hypertension were randomly selected and divided into experimental group and control group. The patients were received CPAP therapy in experimental group,while normal therapy in control group. The polysomnography( PSG) of patients were detected by polysomnography and recorded. The oxyhemoglobin saturation,index of snore and Apnea Hypopnea Index( AHI) of those patients were measured,the difference of systolic blood pressure( SBP) and diastolic blood pressure( DBP) in both groups were compared and analyzed. Results The SBP of patients in experimental group was decreased from( 161. 7 ± 11. 9) mmHg to( 125. 4 ± 10. 3) mmHg,while it was decreased from( 162. 1 ± 12. 0) mmHg to( 140. 9 ± 11. 3) mmHg in control group. The AHI of patients in experimental group was decreased from 45. 9 ± 18. 7 to 4. 5 ± 3. 1,while it was decreased from 46. 0 ± 18. 8 to 21. 4 ± 7. 9 in control group. Conclusion The clinical effect CPAP is better in treating OSAS patients with hypertension. It can improve the symptom of somnolence and decrease the AHI,and also decrease the blood pressure of patients and renew it to normal level.更多还原