Chemokines and their receptors play an important role in many biological processes such as inflammation and angiogenesis.Chemokine CXCL1 is a monomeric protein of chemotaxis cytokines.It usually binds to G protein coupled receptor CXCR2 specifically,and has effects on tumor growth,proliferation,metastasis,invasion and angiogenesis in various cancers.This paper mainly focuses on the role of a subfamily member of chemokine CXCs,CXCL1 in tumors,and of upstream regulatory factors on its expression,in order to e...
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