Both sodium cantharidinate(SCA) and camptothecin(CPT) have been used for clinical tumor therapy.We studied the inhibition on tumor cell growth when combined SCA with CPT both in vitro and in vivo.The results showed that the combination of SCA and CPT enhanced the inhibitory effect of proliferation of A549 lung cancer cell line and Hep3 B hepatoma cell line in vitro.And the CI values of SCA in conjunction with CPT of different concentrations were less than 1,indicating a synergistic effect.Using xenograft mo...
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