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我院开展药物相关基因检测的实践与体会

Practice and experience of pharmacogenetic tests in our hospital

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【作者】 张抗怀王娜蔡艳刘娜李亚仵文英

【Author】 ZHANG Kanghuai;WANG Na;CAI Yan;LIU Na;LI Ya;WU Wenying;Department of Pharmacy,the Second Affiliated Hospital of Medical College of Xi′an Jiaotong University;

【机构】 西安交通大学医学院第二附属医院药剂科

【摘要】 目的回顾我院药物相关基因检测工作开展情况。方法从实验室建立、检测项目和临床应用情况等方面进行阐述。结果我院已开展了30种药物相关基因检测,涉及吉非替尼、伊立替康、氯吡格雷等20余种药物,覆盖医院10余个科室。药物相关基因检测在促进个体化用药方面发挥了积极作用。结论进行药物相关基因检测是临床治疗发展的趋势,医院药师有必要深入开展相关工作,以确保用药安全有效。

【Abstract】 Objective To review the practice of drug related genetic tests in our hospital.Methods Related work including laboratory setup,detection items and clinical use,etc was introduced.Results Our hospital performed 30-type genes tests including 20 drugs such as gefitinib,irinotecan,clopidogrel,etc,and covered over ten clinical divisions.Pharmacogenetic tests in our hospital played an active role in personalized medicine.Conclusion It has become a global trend to apply pharmacogenetic discoveries to patient care.Additional work is required for hospital pharmacists to promote the safe and effective use of medications.

  • 【文献出处】 西北药学杂志 ,Northwest Pharmaceutical Journal , 编辑部邮箱 ,2014年06期
  • 【分类号】R95
  • 【被引频次】5
  • 【下载频次】373
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