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塔黄的化学成分研究

Study on chemical constituents of Rheum nobile Hook.f.et Thoms

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【作者】 施天一廖志新叶润胥廉谦孙洪发纪兰菊

【Author】 SHI Tianyi;LIAO Zhixin;YE Run;XU Lianqian;SUN Hongfa;JI Lanju;School of Chemistry and Chemical Engineering,Southeast University;Northwest Institute of Plateau Biology,Chinese Academy of Sciences;

【机构】 东南大学化学化工学院中国科学院西北高原生物研究所

【摘要】 目的对塔黄的化学成分进行研究。方法通过各种柱色谱对其成分进行分离纯化,通过波谱解析进行结构鉴定。结果从中分离得到8个化合物,分别鉴定为:大黄素(1),大黄酚(2),大黄素甲醚(3),1,8-二羟基-2,3-甲氧基-6-甲基蒽醌(4),大黄酚葡萄糖苷(5),大黄素葡萄糖苷(6),β-谷甾醇(7),胡萝卜素(8)。结论所有化合物均为首次从该植物中分离得到。

【Abstract】 Objective To study the chemical constituents of Rheum nobile Hook.f.et Thoms.Methods The chemical constituents were isolated and purified by various chromatographic techniques.Their structures were determined on the basis of physical properties and spectroscopic data.Results Eight compounds were isolated and elucidated as 1,3,8-trihydroxy-6-methylanthraquinone(1),1,8-dihydroxy-3-meth-oxy-6-methylanthracene-9,10-dione(2),1,8-dihydroxy-3-methyl-anthraquinone(3),1,8-dihydroxy-2,3-dimethoxy-6-methylanthracene-9,10-dione(4),chrysophanol-8-O-β-D-glucopyranoside(5),emodin-8-O-β-D-glucoside(6),β-sitosterol(7),and daucosterol(8).Conclusion All compounds were isolated from this plant for the first time.

【关键词】 大黄属塔黄化学成分
【Key words】 RheumLRheum nobile Hook.f.et Thomschemical constituent
  • 【文献出处】 西北药学杂志 ,Northwest Pharmaceutical Journal , 编辑部邮箱 ,2014年06期
  • 【分类号】R284.1
  • 【被引频次】11
  • 【下载频次】273
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