【摘要】 目的促进绿色化学的发展。方法用α-吡咯烷酮(2)和对甲氧基苯甲酸(4)一步合成茴拉西坦(1)。结果产物结构经元素分析及红外光谱确认,含量及有关物质经高效液相色谱法检测合格。结论报道的合成方法原子利用率高、污染小,是绿色的合成方法。更多还原

【Abstract】 Objective To promote the development of green chemistry.Methods Aniracetam(1)was synthesized fromα-pyrrolidone(2)and p-methoxy-benzoic acid(4)via only one step.Results The structure of the product was confirmed by elemental analysis and infrared spectrometry.The content and related substances of the product was detected by high performance liquid chromatography.Conclusion This synthetic method was featured with a high atom utilization and lower pollution,which could be considered as a green synthetic method.更多还原