【摘要】 以尿素为氢键破坏剂,研究了不同浓度尿素对浸酸绵羊皮胶原纤维的形貌及热稳定性的影响,之后以打破氢键后的胶原为原料,通过检测不同鞣制阶段残留在鞣液中的鞣剂浓度及相应皮胶原的收缩温度,探索了戊二醛向其内部的渗透情况。结果发现:尿素浓度越高,对胶原的形貌及收缩温度影响越大;鞣前胶原的氢键被破坏越严重,戊二醛向其内部渗透越慢、越少,最终鞣制后样品的热稳定性也越差;在戊二醛与胶原的结合力中,氢键发挥着一定的积极作用,但不是主要作用。更多还原

【Abstract】 The influence of urea solution, which employed as a hydrogen bond breaking agent, on the microstructure and thermal stability of sheep skin collagen was investigated. Skin collagen with broken hydrogen bond was tanned with glutaraldehyde, and then the concentration of tanning agent and shrinkage temperature of collagen at different stage was measured. By doing this, the penetration of glutaraldehyde into the sheep skin collagen can be explored. The results showed that both thermal stability of collagen and the penetration rate of glutaraldehyde decreased with the increase in urea concentration. The collagen sample treated with 6 mol/L urea solutions possessed the worst thermal stability in this experiment. All these results suggested hydrogen bond played an important but not primary role in stabilizing the conformation of collagen fiber.更多还原