【摘要】 多不饱和脂肪酸(Polyunsaturated fatty acids,PUFA),尤其是n-6和n-3 PUFAs,不仅是人体必需营养素,在调节和预防人类疾病方面同时发挥着重要作用。n-6和n-3 PUFAs在哺乳动物细胞内不能相互转换,且是动植物细胞膜的重要组成成分,具有不同的生理功能。细胞膜多不饱和脂肪酸组成比例很大程度上由膳食决定,因此平衡膳食中n-6/n-3 PUFAs具有重要意义。本文总结了n-6和n-3 PUFAs的代谢途径和作用机制,结合临床试验,阐述了平衡n-6/n-3 PUFA的重要性。更多还原

【Abstract】 Polyunsaturated fatty acids( PUFAs),especially n-6 and n-3 PUFAs,are not only the body’s essential nutrients,but also play an important role in the regulation and prevention of human diseases. n-6 and n-3 PUFAs can not convert mutually in mammalian cells,having different physiological functions. The composition of polyunsaturated fatty acids in cell membranes is determined largely by diets,so balancing the ratio of n-6 / n-3 PUFAs is very significant. This article summarizes the metabolic pathways and mechanisms of n-6 and n-3 PUFAs,and combines clinical trials,elaborating the importance of a balanced n-6 / n-3 PUFAs ratio.更多还原