【摘要】 目的通过多导胃电图方法探讨幽门螺杆菌(HP)感染与功能性消化不良(FD)的关系。方法 163例FD患儿,包括103例HP感染(A组)、60例无HP感染(B组),同时选22例无消化道症状患儿为对照组(C组)。3组均进行多导胃电图检测,包括正常慢波百分比(N%)、胃动过缓百分比(B%)、胃动过速百分比(T%)、胃动节律不齐百分比(A%),胃电频率及功率包括主频率(DF)及主功率(DP),餐后/餐前胃电主功率比(P/R),分析胃电描记数据。并对A组中84例治疗后HP转阴患儿的治疗前及治疗后胃电参数进行比较。结果 A组与B组比较,不同慢波频率的百分比差异餐后较餐前明显,餐前餐后DF、DP的变化均不明显。84例HP转阴患儿治疗前后比较,不同慢波频率的百分比改善不明显,但餐前餐后DF、DP及P/R改善均较明显。结论多导胃电图显示HP治疗对改善HP感染的FD患儿餐后症状有很大益处。更多还原

【Abstract】 Objective To explore the relationship between H.pylori(HP) infection and the functional dyspepsia(FD) by 4-lead electrogastrography(EGG). Methods The data of the gastric electrical activity of 163 children with FD, including 103 children with HP infection(group A), 60 without HP infection(group B) and 22 healthy controls(group C) were measured by 4-lead EGG, which included normal slow wave percentage(N%), bradygastria percentage(B%), tachygastria percentage(T%) and motilin uneven rhythm percentage(A%). EGG frequency and power examination included the main frequency(DF), the main power(DP) and postprandial/pre-prandial gastric electrical main power ratio(P/R). EGG data was compared between three groups. Results There was significant difference in pre-prandial and postprandial percentage of different slow wave frequency between group A and group B. There were no significant differences in pre-prandial and postprandial changes of DF and DP between group A and group B. There was no significant difference in the pre-prandial and postprandial percentage change of different slow wave frequencies in 84 HP negative patients. But the significant change was found in pre-prandial and postprandial change of DF, DP and P/R. Conclusion The eradication of HP improved the gastric electrical activity and relieved the postprandial symptom in children with functional dyspepsia under HP infection.更多还原