节点文献
疏肝健脾宁心方治疗功能性消化不良随机平行对照研究
Shuganjianpi Ningxin Personalized Medicine Combined Psychotherapy Treatment of Functional Dyspepsia Randomized Parallel Group Study
【摘要】 [目的]观察疏肝健脾宁心方治疗功能性消化不良疗效。[方法]使用随机平行对照方法,将80例门诊患者按就诊顺序编号法分为两组。对照组40例莫沙必利,5mg/次,3次/d,餐前30min口服;氟哌塞吨美利曲辛(黛力新),10.5mg/次,2次/d,口服。治疗组40例1疏肝健脾宁心方(柴胡10g,枳壳、郁金各15g,佛手、白术各10g,茯苓15g,白芍20g,当归10g,合欢皮15g,甘草6g;伴食积加山楂、鸡内金各10g;便秘加厚朴、莱菔子、火麻仁各15g;气虚加黄芪、太子参各30g;有上腹灼热感加石斛、麦冬各15g;兼郁热去当归加蒲公英15g,栀子10g;湿热去当归加黄芩10g;失眠加酸枣仁15g,远志10g),1剂/d,水煎200mL,早晚口服。连续治疗56d为1疗程。观测临床症状、症状积分(GSRS)、抑郁自评量表(SDS)积分、不良反应。连续治疗1疗程(56d),判定疗效。[结果]治疗组痊愈9例,显效20例,有效7例,无效4例,总有效率90.00%。对照组痊愈4例,显效15例,有效12例,无效9例,总有效率77.50%。治疗组疗效优于对照组(P<0.05)。症状积分(GSRS)、抑郁自评量表(SDS)积分改善治疗组优于对照组(P<0.05)。[结论]疏肝健脾宁心方治疗功能性消化不良效果显著,值得推广。
【Abstract】 [Objective] Shuganjianpi ningxin personalized medicine combined psychotherapy treatment of functional dyspepsia.[ Methods] Random parallel control method,80 cases outpatient treatment order numbers were divided into two groups. A control group of 40 patients Mosapride,5mg / time,3 times / d,orally 30 min before a meal;droperidol plug t melitracen piece(Deanxit),10.5mg / times,2 times / d,orally. Treatment group of 40 patients 1 Shuganjianpi ningxin(Chaihu 10 g,Jike,Yujin each 15 g,Foshou,Baizhu each 10 g,Fuling 15 g,Baishao 20 g,Dangui 10 g,Hehuanpi 15 g,Gancao 6g;Bansi plot plus Shanzha,Jineijin each 10g;constipation plus Houpu,Laifuzi,Huomaren each 15g;qi add Huangqi,Taizishen 30g;epigastric burning sensation plus Shihu,Maidong each 15g;and swelter to Dangui add Pugongying each 15 g,Zhizi 10g;heat to Angelica plus Dangui and Huangqi each 10g;insomnia plus Suanzaoren 15 g,Yuanzhi 10g),1 does/ d,decoction 200 mL,sooner or later,oral;2 personalized medicine full-time doctors psychotherapy. 56 d is a continuous course of treatment. Observing clinical symptoms of adverse reactions. After continuous treatment 56 d,to determine efficacy.[ Results] The cure nine cases,effective in 20 cases,7 cases,4 cases,the total efficiency of 90.00%. The control group healed in 4 cases,15 cases markedly effective in 12 cases,9 cases,the total efficiency 77.50%. Treatment group than the control group(P <0.05). Credit card-like(gsrs)and zung Depression Rating Scale(sds)points to improve the treatment group than the control group(P <0.05). [Conclusion] Shuganjianpi ningxin personalized medicine combined psychotherapy treatment of functional dyspepsia effect is significant,it is worth promoting.
【Key words】 Functional dyspepsia; Shuganjianpi ningxin; Mosapride; Droperidol plug t melitracen piece; GSRS; SDS; Randomized parallel group study;
- 【文献出处】 实用中医内科杂志 ,Journal of Practical Traditional Chinese Internal Medicine , 编辑部邮箱 ,2014年09期
- 【分类号】R259
- 【被引频次】4
- 【下载频次】118