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定眩益脑汤治疗痰瘀阻滞型慢性脑供血不足随机平行对照研究

Dingxuan Yinao Soup Treated Phlegm Block Type CCCI Randomized Parallel Group Study

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【作者】 王林文潘晓蓉

【Author】 WANG Linwen;PAN Xiaorong;Graduate School of Guiyang Medical College;Second Affiliated Hospital of Guiyang Medical College,Department of Neurology;

【机构】 贵阳中医学院研究生部贵阳中医学院第二附属医院神经内科

【摘要】 [目的]观察定眩益脑汤治疗痰瘀阻滞型慢性脑供血不足疗效。[方法]使用随机平行对照方法,将90例住院及门诊患者按就诊顺序编号随机分为3组。西药组30例倍他司汀,8mg/次,3次/d。中成药组30例益脉康胶囊,0.3g/次,3次/d。治疗组30例定眩益脑汤(法半夏12g,白术15g,绞股蓝18g,天麻10g,丹参15g,茯苓20g,三七粉吞服2g,大血藤15g,生姜2片,甘草6g);1剂/d,水煎200mL,早中晚口服。连续治疗30d为1疗程。观察临床症状、血脂水平、hs-CRP血清超敏C蛋白、中医证侯疗效指数。治疗1疗程,判定疗效。[结果]治疗组显效15例,有效12例,无效3例,总有效率90.00%。西药组显效9例,有效10例,无效11例,总有效率66.70%。中成药组显效8例,有效10例,无效12例,总有效率63.30%。血脂及hs-CRP三组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]定眩益脑汤治疗痰瘀阻滞型慢性脑供血不足效果显著,值得推广。

【Abstract】 [Objective] Dingxuan Yinao Treated Phlegm blocking effect of chronic cerebral insufficiency.[Methods] Random parallel control method,90 cases of inpatient and outpatient treatment order numbers were randomly divided into three groups.Western group of 30 patients betahistine,8mg / time,3 times / d.Chinese medicine group of 30 patients Yimaikang capsules,0.3g / time,3 times / d.Treatment group of 30 patients Dingxuan Yinao soup(France Pinellia 12g,Bai Zhu 15g,Jiaogulan 18g,Tianma 10g,Salvia 15g,Poria 20g,notoginseng powder swallow 2g,cuneata 15g,ginger 2,licorice 6g);1 / d,decoction 200mL,early in the evening orally.30d is a continuous course of treatment.Clinical symptoms,blood lipid levels,hs-CRP serum high sensitivity C protein,TCM syndrome efficacy index.A course of treatment to determine efficacy.[Results] 15 cases markedly effective in 12 cases,3 cases,the total efficiency of 90.00%.WM group were 9 cases,10 cases,11 cases,the total efficiency of 66.70%.Chinese medicine group 8 cases,10 cases,12 cases,the total efficiency of 63.30%.Lipid and hs-CRP were improved in the three groups(P<0.01),improvement in the treatment group than the control group(P<0.01).[Conclusion] Dingxuan Yinao Treated Phlegm block type CCCI significant effect and should be introduced.

  • 【文献出处】 实用中医内科杂志 ,Journal of Practical Traditional Chinese Internal Medicine , 编辑部邮箱 ,2014年02期
  • 【分类号】R277.7
  • 【被引频次】5
  • 【下载频次】73
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