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脂肪因子在银屑病发病机制中的研究进展
Research advances on the role of adipokines in the pathogenesis of psoriasis
【摘要】 银屑病是一种慢性炎症性皮肤病,患者多伴有系统性代谢性疾病。脂肪组织作为内分泌器官可分泌多种脂肪因子参与多种代谢性疾病和炎症性疾病的发病。目前的研究证实一些脂肪因子可能参与银屑病的发病过程,并且为将来的诊断治疗提供新的生物学标志。
【Abstract】 Psoriasis is a chronic, immune-mediated inflammatory skin disease, which is frequently accompanied by systemic metabolic diseases. As an endocrine organ, adipose tissue can secrete numerous factors called adipokines, which are involved in the pathogenesis of many kinds of metabolic and infl ammatory diseases. Nowadays, some adipokines have been identifi ed to be involved in the pathogenesis of psoriasis, which would be used as new biomarkers for diagnosis and treatment of poriasis in the future.
【基金】 国家自然科学基金项目(81101186);中华医学会皮肤性病学分会励奥皮肤病学研究基金资助课题
- 【文献出处】 实用皮肤病学杂志 ,Journal of Practical Dermatology , 编辑部邮箱 ,2014年04期
- 【分类号】R758.63
- 【被引频次】7
- 【下载频次】210