【摘要】 目的观察脑梗死患者发病前血浆D-二聚体(D-Dimer)、同型半胱氨酸(Hcy)及血黏度的变化,探讨其与脑梗死发生的关系。方法采用回顾性统计调查94例脑梗死患者的检测数据,同时选取本院健康体检者102例作为对照组。免疫比浊法测定血浆D-二聚体和纤维蛋白原(FIB),酶法测定Hcy,放射免疫法测定叶酸(FA)及维生素B12(VitB12)含量。结果脑梗死患者发病前72h内血浆D-二聚体、FIB及Hcy水平显著高于对照组(P<0.05),FA、VitB12水平明显低于对照组(P<0.05),患者全血及血浆黏度均高于对照组(P<0.05)。结论血黏度增加伴有高D-二聚体和Hcy血症可能是脑梗死的促发因素之一。更多还原

【Abstract】 Objective To investigate the relationship between plasma D-D dimer,homocysteine(Hcy),blood viscosity levels and cerebral infarction. Methods Ninety-four patients with cerebral infarction and 102healthy persons(control group)were enrolled and observed.The levels of D-D dimer,fibrinogen(FIB),Hcy,folic acid(FA),VitB12 were detected by immune turbidimetry,enzyme and RIA respectively(0-72hbefore the stroke).Results The levels of D-dimer,FIB,Hcy and blood viscosity were significantly higher and the plasma levels of FA and VitB12 were lower in the patients with cerebral infarction than those in control group(P<0.05). ConclusionsHigh levels of plasma D-dimer,homocysteine and blood viscosity may be the risk factors for stroke.更多还原