【摘要】 目的:研究氧化亚氮(N2O)镇静在儿童牙科畏惧症(DF)患者治疗中应用的效果并探讨N2O镇静的应用浓度。方法:对66例患儿应用N2O进行镇静,观察不同浓度N2O应用前后的心率(HR)和氧饱和度(SpO2)变化,分别采用RamSay镇静评分和Houpt行为量表评分对镇静治疗浓度进行评价。结果:患儿镇静显效所需N2O最低浓度为25%~70%(49.6%±12.1%);最大耐受浓度为35%~70%(56.4%±10.1%)。N2O产生的Ramsay镇静评分最大值为(2.3±0.6),患儿在治疗过程中均对医生的口头指令有所响应。患儿吸入N2O/O2混合气体后前后HR(次/min)分别为(89.0±15.8)和(83.4±12.1)(P<0.05),Houpt行为量表评分分别为(1.2±0.6)和(4.4±1.1)(P<0.01),能更好地配合治疗,SpO2分别为(98.4±0.9)%和(99.1±0.9)%(P>0.05)。结论:25%~70%的N2O用于儿童牙科畏惧是安全有效的。更多还原

【Abstract】 Objective: To study the effects of nitrous oxide( N2O) sedation in the management of dental fear( DF) for dental treatments of children. Methods: 66 cases of pediatric patients( aged 6 to 14 years) were given N2O sedation for dental treatments. The heart rate( HR) and oxygen saturation( SpO2) were measured before and after N2O inhalation. N2O effective concentration was evaluated by Ramsay sedation score and Houpt behavior score. Results: The effective concentration of N2O sedation was 25%- 70%( 49. 6% ±12. 1%),the maximum endurance concentration 35%-70%( 56. 4% ±10. 1%). The Ramsy scores of N2O sedation was( 2. 3 ± 0. 6). After N2O inhalation,all patients could receive verbal demand during the treatments. The HR decreased( P < 0. 05) and the Houpt behavior score increased( P < 0. 01). Before and after N2O inhalation SpO2had no significant difference( P > 0. 05). Conclusion: N2O inhalation at 25%- 70% is safe and effective in the management of DF for dental treatments of children.更多还原