Using salicylic acid and methanol as raw materials,methyl salicylate was respectively synthesized in concentrated sulfuric acid or potassium hydrogen sulfate.Effect of mole ratio of acid to alcohol,reaction time and catalyst dosage on yield of the ester was investigated.The results show that,using potassium bisulfate as catalyst,n(salicylic acid):n(methanol) = 1:5,reaction time 5 h,the highest yield of methyl salicylate can be obtained,average yield can reach to 70%.