【摘要】 目的 探讨35岁以下年轻妇女子宫颈癌(年轻宫颈癌)综合治疗的临床疗效。方法 52例年轻宫颈癌术前行子宫动脉灌注化疗栓塞治疗(介入治疗)。其中50例介入治疗后行广泛子宫切除+盆腔淋巴结清扫术。评估介入治疗的临床疗效。术后病理示有相关高危因素者,补充放化疗。结果 介入治疗后子宫颈肿瘤明显缩小,差异有统计学意义(P<0.05);全组有效率88.5%;手术切除率96.2%;淋巴结转移率26.9%;全组2、5年生存率分别为91.5%、71.2%。肿瘤分期、肿瘤大小、淋巴结转移、脉管受侵、术后补充放化疗与预后相关(P<0.05)。结论 综合治疗能提高年轻宫颈癌患者的生存率及生活质量:术后病理结果示有相关危险因素者,应补充放化疗。更多还原

【Abstract】 Objective To investigate the clinical therapeutic effect of comprehensive treatment in young women with cervical carcinoma.Methods A total of 52 young women with cervical carcinoma were treated with uterine artery chemoembolization.50 cases underwent radical hysterectomy and pelvic lymphadenectomy after interventional therapy.The patients with pathological risk factors were given supplementary radiotherapy.Results The clinical overall response rate was 88.5%.96.2% of patients underwent surgery and lymph node metastasis rate was 26.9%.The 2,5 year overall survival rates of patients were 91.5%,71.2% respectively.Conclusion The comprehensive treatment can improve overall survival rate and quality of life for young woman with cervical carcinoma,Postoperative patients with pathologically related risk factors should be treated with supplement chemoradiotherapy.更多还原